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Micropharmacology SystemPeriIont

  • Non-invasive drug delivery
  • Simultaneous blood perfusion measurement
  • Compatible with all Perimed instruments
The PeriIont Micropharmacology System has not yet received a USA Premarket 
Notification (510(k)) and, due to this, an IRB (Institutional Review Board) approval 
is required for measurements on humans in the USA.




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PeriIont Micropharmacology System

The PeriIont Micropharmacology System is an iontophoresis system that can deliver minute volumes of drugs non-invasively in a controlled fashion. Together with the laser Doppler or the laser Speckle (LASCA) technique, vascular responses to the drug can be studied. Depending on the choice of drug, endothelium dependent and endothelium independent vasodilation can be studied.

The PeriIont Micropharmacology System is available for the PeriFlux System 5000 and the PeriCam PSI System. To further enhance its usability, the latest generation iontophoresis device, PF 751 PeriIont USB Power Supply, is operated using the PeriIont Software making it possible to automate the iontophoresis procedure.

Features

PF 751 PeriIont USB Power Supply

The PeriIont Micropharmacology System is available for the PeriFlux System 5000 and the PeriCam PSI System. To further enahance its usability, the latest generation iontophoresis device, PF 751 PeriIont USB Power Supply, is operated using the PeriIont Software making it possible to automate the iontophoresis procedure.

Iontophoresis with LDPM

The PeriIont Micro Pharmacology System can be used with the PeriFlux System 5000 and the thermostatic probe 481, a specially designed probe for iontophoresis. The shape of the probe fits perfectly with PF 383 Drug delivery electrode and allows for simultaneous iontophoresis and efficient heating of the skin.

Iontophoresis with imaging

The PeriIont Micro Pharmacology System can be used with the laser speckle imager PeriCam PSI, using the drug delivery electrode LI 611. The transparent window of drug delivery electrode LI 611 allows for blood perfusion measurement of the whole iontophorezed area.


PeriIont Software

PeriIont Software (PIS) is an application software operating the PF 751 PeriIont USB Power Supply. In the PeriIont Software it is possible to create and save protocols used for iontophoresis. This automates the general workflow for the end-user, ensuring higher reproducibility.

PeriIont Software (PIS) is simple and straightforward, and clearly displays the current step as well as an overview of the chosen protocol. Graphical views of the resistance, voltage and current are also shown.

Consumables

PeriIont for LDPM

The only consumables required for the PeriIont Micro Pharmacology System are drug delivery electrodes and dispersive electrodes. Each iontophoresis test requires one drug delivery electrode (PF 383 Drug Delivery Electrode) together with one counter-electrode (PF 384 Dispersive Electrode).

PeriIont for Imagers

The only consumables required for the PeriIont Micro Pharmacology System are drug delivery electrodes and dispersive electrodes. Each iontophoresis test requires one drug delivery electrode (LI 611 Drug Delivery Electrode) together with one counter-electrode (PF 384 Dispersive Electrode).

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Improving quality of life since 1981

Perimed AB, established in 1981, provides instruments, software and expertise to enable assessment of the microcirculation. We utilize laser Doppler, laser speckle (LASCA) and transcutaneous oxygen (tcpO2 or TCOM), to accurately monitor and quantify blood perfusion and tissue oxygenation in real-time. Our modular PeriFlux System 5000 and PeriFlux 6000, the latest generation of our PeriFlux System, are excellent choices for diagnosing Peripheral Arterial Disease (PAD) and Critical Limb Ischemia (CLI) or for assessing wound healing potential in your vascular patients. Our blood perfusion imager PeriCam PSI System allows you to investigate spatial distribution, for example during cortical spreading depression.