Many patients at risk for peripheral arterial disease (PAD) present with substantial comorbidities, which increases the risk for cardiovascular events and makes diagnosis more complex. If the patient presents with a set of different overlapping problems (e.g., diabetes, chronic kidney disease, hypertension) then it is unlikely that just one vascular test will answer all questions. The solution is simple; combine different vascular tests to get a good picture of both the macrovascular and microvascular status in the limbs.
Patients with diabetes or chronic kidney disease might have medial calcification and macrovascular/microvascular problems. A combination of toe pressure, PVR and tcpO2 is the only option.
All chronic limb-threatening ischemia (CLTI) patients should be evaluated using both toe pressure and tcpO2 according to recent findings.
It is important to make sure that perfusion is restored in both the macro- and microcirculation following revascularization.
Better for the patient to get all hemodynamic tests done in one quick visit.
Easier for the vascular staff to interpret the report when all tests were performed at the same time and under the same conditions.
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