Peripheral Arterial Disease (PAD)

Peripheral arterial disease (PAD) is a condition caused by obstruction of the peripheral arteries, leading to an increased risk for cardiovascular events and premature death. The classic PAD symptom is intermittent claudication or walking pain, but notably two-thirds of all patients are asymptomatic. Early diagnosis and treatment using noninvasive vascular tests are crucial to saving lives.

With an increasing population of patients with diabetes that is often asymptomatic and with falsely normal or high ankle-brachial index (ABI) values, detecting PAD has changed in recent years. For reliable non-invasive vascular tests, look instead to toe pressure, pulse volume recording (PVR) and transcutaneous oximetry (tcpO2).

Why is the diagnosis more complex in patients with diabetes?
  • Neuropathy
  • Longer & multiple lesions
  • Asymptomatic
  • Less collateral flow
  • Below the knee
  • More aggressive
  • Microcirculatory issues
  • Perfusion deficit in foot more severe
  • Peripheral Arterial Disease – Diagnosis in patients with diabetes. By Prof. R. Hinchliffe

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