Peripheral Arterial Disease (PAD)

Peripheral arterial disease (PAD) is a condition caused by obstruction of the peripheral arteries, leading to an increased risk for cardiovascular events and premature death. The classic PAD symptom is intermittent claudication or walking pain, but notably two-thirds of all patients are asymptomatic. Early diagnosis and treatment using noninvasive vascular tests are crucial to saving lives.

Diabetic foot disease, mainly due to neuropathy, peripheral arterial disease, and/or infection, often leads to ulceration and possible subsequent limb amputation. It is one of the most costly complications of diabetes.

With an increasing population of patients with diabetes that is often asymptomatic and with falsely normal or high ankle-brachial index (ABI) values, detecting PAD has changed in recent years. For reliable non-invasive vascular tests, look instead to toe pressure, pulse volume recording (PVR) and transcutaneous oximetry (tcpO2).

Why is the diagnosis more complex in patients with diabetes?
  • Neuropathy
  • Longer & multiple lesions
  • Asymptomatic
  • Less collateral flow
  • Below the knee
  • More aggressive
  • Microcirculatory issues
  • Perfusion deficit in foot more severe

Instructional Video for the PeriFlux 6000 Combined System

Assessment of microcirculation in the diabetic foot with PeriCam PSI NR

ESVS Educational Video – Professor Maarit Venermo

Peripheral Arterial Disease – Diagnosis in patients with diabetes. By Prof. R. Hinchliffe

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