Iontophoresis is a technique to transport charged molecules or drugs across a tissue barrier. Combined with the laser Doppler or laser speckle techniques, iontophoresis is a valuable tool for diagnosis and studying endothelial dysfunction.

Features PeriFlux System 5000 Features PeriCam PSI NR
Single-point monitoring. Imaging of larger area.
Low volumes of drug solution needed. Transparent drug delivery chamber.
Standardized skin temperature during experiment. Calculation of flare statistics.

Iontophoresis is a technique that can be used to transport drugs in ionic form across intact skin. Depending on the chosen drug, this may or may not affect the local blood perfusion. The technique is based on the principle that an electric potential will cause ions in a solution to migrate according to their electrical charges.

PeriIont Micro Pharmacology System is an iontophoresis system that can deliver minute volumes of drugs noninvasively in a controlled manner. Together with the laser Doppler or the laser speckle contrast analysis (LASCA) technique, the vascular responses to the drug can be studied while it is being delivered. PeriIont Micro Pharmacology System is a useful system for studying endothelial dysfunction, and it is available for PeriFlux System 5000 and PeriCam PSI System.

PeriIont Micropharmacology System

PeriIont Micropharmacology System is a versatile accessory for studying microcirculatory responses to noninvasively delivered drugs. The system is offered as a complete kit with everything you need to start the measurements.

Endothelial Dysfunction

Iontophoresis is an excellent method to study the endothelium and assess the patient’s endothelium-dependent and endothelium-independent vasodilation.

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