See the video below for an example of how the PeriCam PSI can be used in the clinic6: https://www.jove.com/video/58535/a-novel-approach-to-monitoring-graft-neovascularization-human Here you can find two cases, which were captured by LSCI:
Case 1: PORH-test on human gingiva
Figure 1 Regional differences in resting blood flow in the maxillary front area. Perfusion is highest in the interdental area above the papilla and lowest in the midbuccal area. Papillary blood flow is in-between them. Due to the bright wet surface, reflections can be observed. Spatial and temporal changes in human gingival blood flow during and after transient compression. Laser speckle images at four privileged moments of a measurement applying 5 s horizontal compression on the gingiva at tooth 12. Blood flow during baseline (A), during compression (B), at the hyperemic peak (C) and twenty minutes after releasing the pressure (D).
During the temporary compression process, the attached gingiva was pressed to the subjacent bone, resulting in an occlusion in the vessels of the mucoperiosteum, thereby causing transient ischemia. As a reaction to the brief period of ischemia a temporary increase in gingival blood flow occured, called reactive hyperemia. Blood flow returned to the baseline 20 minutes after the release of compression.
Case 2: Flap assessment in oral mucosa
Figure 2 Representative photographs and LSCI images on a patient following modified coronally advanced tunnel surgery with free gingival grafts at tooth 41 and 31 (labelled). Images representing from the preoperative perfusion and showing the wound healing and perfusion on day 3, 6, 10, 14 and 30.
LSCI method allow us to study the physiology of mucosa in the oral cavity, also to follow up the healing of different type of surgical methods and the behavior of materials and grafts. János Vág PhD, d.m.d. firstname.lastname@example.org Eszter Molnár d.m.d. email@example.com Réka Fazekas d.m.d. firstname.lastname@example.org