{"id":1030,"date":"2024-12-20T13:53:33","date_gmt":"2024-12-20T13:53:33","guid":{"rendered":"http:\/\/www.perimed-instruments.com\/us\/?post_type=application&#038;p=1030"},"modified":"2026-08-05T07:32:16","modified_gmt":"2026-08-05T07:32:16","slug":"skin-perfusion-pressure-spp","status":"publish","type":"application","link":"https:\/\/www.perimed-instruments.com\/us\/applications\/clinical-exams\/skin-perfusion-pressure-spp\/","title":{"rendered":"Skin perfusion pressure \u2014 SPP"},"content":{"rendered":"<section class=\"relative w-full mx-auto pt-24 2xl:pt-24 pb-24 2xl:pb-24 none\">\n                                                \n                                        <div class=\"sec-bg sec-bg-laptop absolute top-0 inset-0 flex justify-center overflow-hidden bg-no-repeat w-full h-full pointer-events-none z-[-1]\" style=\"background-image: url(https:\/\/www.perimed-instruments.com\/us\/wp-content\/uploads\/sites\/3\/bg-hero-white-blur-right.webp);background-size:cover;background-position:center;\"><\/div>\n                                        <div class=\"sec-bg sec-bg-mobile absolute top-0 inset-0 flex justify-center overflow-hidden bg-no-repeat w-full h-full pointer-events-none z-[-1]\" style=\"background-image: url(https:\/\/www.perimed-instruments.com\/us\/wp-content\/uploads\/sites\/3\/bg-hero-white-blur-right.webp);background-size:cover;background-position:center;\"><\/div>\n                                        <div class=\"sec-bg sec-bg-wide absolute top-0 inset-0 flex justify-center overflow-hidden bg-no-repeat w-full h-full pointer-events-none z-[-1]\" style=\"background-image: url(https:\/\/www.perimed-instruments.com\/us\/wp-content\/uploads\/sites\/3\/bg-hero-white-blur-right.webp);background-size:cover;background-position:center;\"><\/div>\n                                        \n\n        <div class=\"section__content  max-w-screen-xl px-4 mx-auto sec_no_tabs\" >\n            \n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-7387b849 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<div class=\"wp-block-group is-content-justification-left is-layout-constrained wp-container-core-group-is-layout-a6afe6a7 wp-block-group-is-layout-constrained\"><div class=\"yoast-breadcrumbs\"><span><span><a href=\"https:\/\/www.perimed-instruments.com\/us\/\">Home<\/a><\/span> \/ <span><a href=\"https:\/\/www.perimed-instruments.com\/us\/applications\/\">Applications<\/a><\/span> \/ <span><a href=\"https:\/\/www.perimed-instruments.com\/us\/applications\/clinical-exams\/\">Clinical exams<\/a><\/span> \/ <span class=\"breadcrumb_last\" aria-current=\"page\">Skin perfusion pressure \u2014 SPP<\/span><\/span><\/div>\n\n\n<h1 id=\"h-skin-perfusion-pressure-spp\" class=\"wp-block-heading pb-8 has-h-1-font-size\">Skin perfusion pressure \u2014 SPP<\/h1>\n\n\n\n<p class=\"has-text-hero-font-size wp-block-paragraph\">SPP is a noninvasive method that leverages laser Doppler to measure blood perfusion in the microcirculation. It is primarily used in clinical (and clinical research) settings to assess wound healing potential \u2014 especially in patients with chronic conditions such as diabetic foot <a href=\"#references\"><sup>[1]<\/sup><\/a>.<\/p>\n\n\n\n<p class=\"has-text-hero-font-size wp-block-paragraph\">One of the main advantages of SPP is that it is not affected by vascular calcification or anatomical structure. When clinical conditions \u2014 such as wounds on the sole or amputated toes \u2014 preclude the application of toe pressure or TcpO2, SPP is a viable alternative.<\/p>\n\n\n<div class=\"gn-spacer-block pb-10\">\n    <\/div>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link wp-element-button\" href=\"#learn-more\">Learn more<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-vertically-aligned-center is-layout-flow wp-block-column-is-layout-flow\">\n<figure class=\"wp-block-image alignright size-full is-style-rounded\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"550\" src=\"https:\/\/www.perimed-instruments.com\/us\/wp-content\/uploads\/sites\/3\/periflux-6000-SPP-probe-foot-plantar-1-1.webp\" alt=\"periflux 6000 SPP-probe foot plantar\" class=\"wp-image-2288\" srcset=\"https:\/\/www.perimed-instruments.com\/us\/wp-content\/uploads\/sites\/3\/periflux-6000-SPP-probe-foot-plantar-1-1.webp 800w, https:\/\/www.perimed-instruments.com\/us\/wp-content\/uploads\/sites\/3\/periflux-6000-SPP-probe-foot-plantar-1-1-300x206.webp 300w, https:\/\/www.perimed-instruments.com\/us\/wp-content\/uploads\/sites\/3\/periflux-6000-SPP-probe-foot-plantar-1-1-768x528.webp 768w, https:\/\/www.perimed-instruments.com\/us\/wp-content\/uploads\/sites\/3\/periflux-6000-SPP-probe-foot-plantar-1-1-769x530.webp 769w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n<\/div>\n<\/div>\n\n\n        <\/div>\n    <\/section>\n\n\n<section class=\"relative w-full mx-auto pt-24 2xl:pt-24 pb-12 2xl:pb-12 none\" id=\"learn-more\">\n                        \n\n        <div class=\"section__content  max-w-4xl px-4 mx-auto sec_no_tabs\" >\n            \n\n<h2 id=\"h-spp-with-periflux-6000\" class=\"wp-block-heading has-h-2-font-size\">SPP with PeriFlux 6000<\/h2>\n\n\n\n<p class=\"has-text-20-font-size wp-block-paragraph\">It\u2019s possible to carry out toe pressure and SPP in a single patient visit.<\/p>\n\n\n<div class=\"gn-spacer-block pb-8\">\n    <\/div>\n\n\n\n<figure class=\"wp-block-image aligncenter size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"417\" src=\"https:\/\/www.perimed-instruments.com\/us\/wp-content\/uploads\/sites\/3\/periflux_6000_combined_system_skin_perfusion_pressure_setup.webp\" alt=\"periflux 6000 combined system skin perfusion pressure setup\" class=\"wp-image-1031\" style=\"width:864px;height:auto\" srcset=\"https:\/\/www.perimed-instruments.com\/us\/wp-content\/uploads\/sites\/3\/periflux_6000_combined_system_skin_perfusion_pressure_setup.webp 800w, https:\/\/www.perimed-instruments.com\/us\/wp-content\/uploads\/sites\/3\/periflux_6000_combined_system_skin_perfusion_pressure_setup-300x156.webp 300w, https:\/\/www.perimed-instruments.com\/us\/wp-content\/uploads\/sites\/3\/periflux_6000_combined_system_skin_perfusion_pressure_setup-768x400.webp 768w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n<div class=\"gn-spacer-block pb-8\">\n    <\/div>\n\n\n\n<p class=\"has-p-regular-font-size wp-block-paragraph\">SPP can be measured at multiple sites: on the foot (plantar, dorsal, and toes), on the ankle, and above and below the knee. Blood flow is occluded by placing a pressure cuff over the probe and inflating it above the patient\u2019s resting systolic pressure. The cuff is then gradually deflated until microcirculatory flow returns \u2014 this is the SPP value and is measured in millimeters of mercury (mmHg).<\/p>\n\n\n\n<p class=\"has-p-regular-font-size wp-block-paragraph\">SPP can help identify ischemic areas (by, for example, using the angiosome concept). Comparing SPP measurements in areas adjacent to a non-healing ulcer can reveal microcirculatory vascular deficiencies.<\/p>\n\n\n        <\/div>\n    <\/section>\n\n\n<section class=\"relative w-full mx-auto pt-24 2xl:pt-24 pb-12 2xl:pb-12 none\" id=\"how-to\">\n                                                \n                                        <div class=\"sec-bg sec-bg-laptop absolute top-0 inset-0 flex justify-center overflow-hidden bg-no-repeat w-full h-full pointer-events-none z-[-1]\" style=\"background-image: url(https:\/\/www.perimed-instruments.com\/us\/wp-content\/uploads\/sites\/3\/gradient-pattern-1.webp);background-size:cover;background-position:center;\"><\/div>\n                                        <div class=\"sec-bg sec-bg-mobile absolute top-0 inset-0 flex justify-center overflow-hidden bg-no-repeat w-full h-full pointer-events-none z-[-1]\" style=\"background-image: url(https:\/\/www.perimed-instruments.com\/us\/wp-content\/uploads\/sites\/3\/gradient-pattern-1.webp);background-size:cover;background-position:center;\"><\/div>\n                                        <div class=\"sec-bg sec-bg-wide absolute top-0 inset-0 flex justify-center overflow-hidden bg-no-repeat w-full h-full pointer-events-none z-[-1]\" style=\"background-image: url(https:\/\/www.perimed-instruments.com\/us\/wp-content\/uploads\/sites\/3\/gradient-pattern-1.webp);background-size:cover;background-position:center;\"><\/div>\n                                        \n\n        <div class=\"section__content  max-w-4xl px-4 mx-auto sec_no_tabs\" >\n            \n\n<h5 id=\"h-how-to-carry-out-spp-with-periflux-6000\" class=\"wp-block-heading has-h-2-font-size\">How to carry out SPP with PeriFlux 6000<\/h5>\n\n\n\n<figure class=\"wp-block-embed is-type-video is-provider-vimeo wp-block-embed-vimeo wp-embed-aspect-16-9 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<iframe loading=\"lazy\" title=\"How to carry out SPP with PeriFlux 6000\" src=\"https:\/\/player.vimeo.com\/video\/1215715681?dnt=1&amp;app_id=122963\" width=\"500\" height=\"281\" frameborder=\"0\" allow=\"autoplay; fullscreen; picture-in-picture; clipboard-write; encrypted-media; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\"><\/iframe>\n<\/div><\/figure>\n\n\n        <\/div>\n    <\/section>\n\n\n<section class=\"relative w-full mx-auto  pb-12 2xl:pb-12 none\">\n                        \n\n        <div class=\"section__content  max-w-4xl px-4 mx-auto sec_no_tabs\" >\n            \n\n<h3 id=\"h-when-to-use-spp\" class=\"wp-block-heading has-h-2-font-size\">When to use SPP<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Not all patients are the same, toe pressure, for example, isn\u2019t feasible for a person whose toes have been amputated. For patients with edema, callouses, or wounds on the sole or plantar region, SPP is the most applicable means for measuring the microcirculation.<\/p>\n\n\n<div class=\"gn-spacer-block pb-8\">\n    <\/div>\n\n\n\n<h3 id=\"h-interpreting-spp-results\" class=\"wp-block-heading has-h-3-font-size\">Interpreting SPP results<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">The 2023 update of the IWGDF guidelines<a href=\"#references\"> <sup>[2]<\/sup><\/a>, includes SPP values for wound-healing prognosis, stating that values \u2265 40 mmHg can increase the probability of healing by up to 30%.<\/p>\n\n\n        <\/div>\n    <\/section>\n\n\n\n<p class=\"wp-block-paragraph\" id=\"spp-tcpo2-guide\"><\/p>\n\n\n<section class=\"relative w-full mx-auto pt-24 2xl:pt-24 pb-12 2xl:pb-12 none\" id=\"how-to\">\n                                                \n                                        <div class=\"sec-bg sec-bg-laptop absolute top-0 inset-0 flex justify-center overflow-hidden bg-no-repeat w-full h-full pointer-events-none z-[-1]\" style=\"background-image: url(https:\/\/www.perimed-instruments.com\/us\/wp-content\/uploads\/sites\/3\/gradient-pattern-1.webp);background-size:cover;background-position:center;\"><\/div>\n                                        <div class=\"sec-bg sec-bg-mobile absolute top-0 inset-0 flex justify-center overflow-hidden bg-no-repeat w-full h-full pointer-events-none z-[-1]\" style=\"background-image: url(https:\/\/www.perimed-instruments.com\/us\/wp-content\/uploads\/sites\/3\/gradient-pattern-1.webp);background-size:cover;background-position:center;\"><\/div>\n                                        <div class=\"sec-bg sec-bg-wide absolute top-0 inset-0 flex justify-center overflow-hidden bg-no-repeat w-full h-full pointer-events-none z-[-1]\" style=\"background-image: url(https:\/\/www.perimed-instruments.com\/us\/wp-content\/uploads\/sites\/3\/gradient-pattern-1.webp);background-size:cover;background-position:center;\"><\/div>\n                                        \n\n        <div class=\"section__content  max-w-4xl px-4 mx-auto sec_no_tabs\" >\n            \n\n<h6 id=\"h-download-our-ebook\" class=\"wp-block-heading has-h-3-font-size\">Download our eBook<\/h6>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" src=\"https:\/\/www.perimed-instruments.com\/wp-content\/uploads\/Perimed-SPP-TcpO2-practical-guide-1024x724.webp\" alt=\"\" class=\"wp-image-3990\"\/><\/figure>\n\n\n<div class=\"gn-spacer-block pb-8\">\n    <\/div>\n\n\n\n<div class=\"hs-cta-embed hs-cta-simple-placeholder hs-cta-embed-187324364950\" style=\"max-width:100%; max-height:100%; width:182px;height:50.390625px\" data-hubspot-wrapper-cta-id=\"187324364950\">\n  <a href=\"https:\/\/www.perimed-instruments.com\/us\/wp-content\/uploads\/sites\/3\/Perimed-SPP-TcpO2-practical-guide.pdf\" target=\"_blank\" rel=\"noopener\" crossorigin=\"anonymous\">\n    <img decoding=\"async\" alt=\"Download eBook\" loading=\"lazy\" src=\"https:\/\/no-cache.hubspot.com\/cta\/default\/19961763\/interactive-187324364950.png\" style=\"height: 100%; width: 100%; object-fit: fill\" onerror=\"this.style.display='none'\">\n  <\/a>\n<\/div>\n\n\n        <\/div>\n    <\/section>\n\n\n<section class=\"relative max-w-screen-xl mx-auto  pb-28 none\">\n                        \n\n        <div class=\"section__content  max-w-4xl px-4 mx-auto sec_no_tabs\" >\n            \n<section class=\"relative w-full radius-8 mx-auto pt-40 2xl:pt-48 pb-40 2xl:pb-48 none\">\n                                                \n                                        <div class=\"sec-bg sec-bg-laptop absolute top-0 inset-0 flex justify-center overflow-hidden bg-no-repeat w-full h-full pointer-events-none z-[-1]\" style=\"background-image: url(https:\/\/www.perimed-instruments.com\/us\/wp-content\/uploads\/sites\/3\/lower-bg-quote.webp);background-size:100% 100%;background-position:center;\"><\/div>\n                                        <div class=\"sec-bg sec-bg-mobile absolute top-0 inset-0 flex justify-center overflow-hidden bg-no-repeat w-full h-full pointer-events-none z-[-1]\" style=\"background-image: url(https:\/\/www.perimed-instruments.com\/us\/wp-content\/uploads\/sites\/3\/lower-bg-quote.webp);background-size:cover;background-position:center;\"><\/div>\n                                        <div class=\"sec-bg sec-bg-wide absolute top-0 inset-0 flex justify-center overflow-hidden bg-no-repeat w-full h-full pointer-events-none z-[-1]\" style=\"background-image: url(https:\/\/www.perimed-instruments.com\/us\/wp-content\/uploads\/sites\/3\/lower-bg-quote.webp);background-size:100% 100%;background-position:center;\"><\/div>\n                                        \n\n        <div class=\"section__content  max-w-4xl px-4 mx-auto sec_no_tabs\" >\n            \n\n<p class=\"has-text-align-center has-text-hero-font-size wp-block-paragraph\">The main advantage of SPP is that it is not affected by vascular calcification and anatomical structure. <a href=\"#references\"><sup>[3]<\/sup><\/a><\/p>\n\n\n        <\/div>\n    <\/section>\n\n\n        <\/div>\n    <\/section>\n\n\n<section class=\"relative w-full mx-auto pt-12 pb-12 none\">\n                                                \n                                        <div class=\"sec-bg sec-bg-laptop absolute top-0 inset-0 flex justify-center overflow-hidden bg-no-repeat w-full h-full pointer-events-none z-[-1]\" style=\"background-image: url(https:\/\/www.perimed-instruments.com\/us\/wp-content\/uploads\/sites\/3\/2024\/12\/background_tall_blur_1.webp);background-size:cover;background-position:center;\"><\/div>\n                                        <div class=\"sec-bg sec-bg-mobile absolute top-0 inset-0 flex justify-center overflow-hidden bg-no-repeat w-full h-full pointer-events-none z-[-1]\" style=\"background-image: url(https:\/\/www.perimed-instruments.com\/us\/wp-content\/uploads\/sites\/3\/2024\/12\/background_tall_blur_1.webp);background-size:cover;background-position:center;\"><\/div>\n                                        <div class=\"sec-bg sec-bg-wide absolute top-0 inset-0 flex justify-center overflow-hidden bg-no-repeat w-full h-full pointer-events-none z-[-1]\" style=\"background-image: url(https:\/\/www.perimed-instruments.com\/us\/wp-content\/uploads\/sites\/3\/2024\/12\/background_tall_blur_1.webp);background-size:cover;background-position:center;\"><\/div>\n                                        \n\n        <div class=\"section__content  max-w-screen-xl px-4 mx-auto sec_no_tabs\" >\n            \n\n<h2 id=\"h-related-products-and-applications\" class=\"wp-block-heading has-h-2-font-size\">Related products and applications<\/h2>\n\n\n<div class=\"gn-spacer-block pb-5\">\n    <\/div>\n\n\n<div class=\"products-grid grid grid-cols-1 md:grid-cols-3 gap-6 \"\n        >\n                    \n            <div class=\"product-card bg-white rounded-[7px] overflow-hidden\">\n                                    <a href=\"https:\/\/www.perimed-instruments.com\/us\/products\/periflux-vascular-systems\/periflux-6000\/combined\/\">\n                                                    <div class=\"aspect-w-16 aspect-h-9\">\n                        <img decoding=\"async\" src=\"https:\/\/www.perimed-instruments.com\/us\/wp-content\/uploads\/sites\/3\/periflux-6000-combined-system-2.webp\" alt=\"PeriFlux 6000 Combined System\" class=\"object-cover w-full h-full\">\n                    <\/div>\n                \n                <div class=\"p-6\">\n                    <div style=\"display: none;\">product-type <\/div>\n                    \n                    <h3 class=\"pb-2\">\n                        PeriFlux 6000 Combined System\n                    <\/h3>\n\n                                            <div class=\"text-black mb-8 text-lg product-excerpt\">\n                            A powerful, all-in-one vascular care solution designed to deliver comprehensive macro- and microvascular measurements primarily for clinical use.\n                        <\/div>\n                    \n                                            <div>\n                            <span class=\"inline-flex items-center text-black product-read-more-link\">\n                                <span class=\"mr-6 font-medium\">\n                                    Show product\n                                <\/span>\n                                <img decoding=\"async\" src=\"https:\/\/www.perimed-instruments.com\/us\/wp-content\/themes\/perimed\/public\/images\/arrow-right.d1b3f7.svg\" alt=\"Arrow right\" class=\"mt-1 w-4 h-4\">\n                                <span class=\"sr-only\">about PeriFlux 6000 Combined System<\/span>\n                            <\/span>\n                        <\/div>\n                                    <\/div>\n                                    <\/a>\n                            <\/div>\n                    \n            <div class=\"product-card bg-white rounded-[7px] overflow-hidden\">\n                                    <a href=\"https:\/\/www.perimed-instruments.com\/us\/products\/periflux-vascular-systems\/periflux-6000\/pressure\/\">\n                                                    <div class=\"aspect-w-16 aspect-h-9\">\n                        <img decoding=\"async\" src=\"https:\/\/www.perimed-instruments.com\/us\/wp-content\/uploads\/sites\/3\/periflux-6000-pressure-bg-2.webp\" alt=\"PeriFlux 6000 Pressure System\" class=\"object-cover w-full h-full\">\n                    <\/div>\n                \n                <div class=\"p-6\">\n                    <div style=\"display: none;\">product-type <\/div>\n                    \n                    <h3 class=\"pb-2\">\n                        PeriFlux 6000 Pressure System\n                    <\/h3>\n\n                                            <div class=\"text-black mb-8 text-lg product-excerpt\">\n                            For clinical\/research practice focusing on pressure exams like TBI, ABI, SPP, and segmental pressure.\n                        <\/div>\n                    \n                                            <div>\n                            <span class=\"inline-flex items-center text-black product-read-more-link\">\n                                <span class=\"mr-6 font-medium\">\n                                    Show product\n                                <\/span>\n                                <img decoding=\"async\" src=\"https:\/\/www.perimed-instruments.com\/us\/wp-content\/themes\/perimed\/public\/images\/arrow-right.d1b3f7.svg\" alt=\"Arrow right\" class=\"mt-1 w-4 h-4\">\n                                <span class=\"sr-only\">about PeriFlux 6000 Pressure System<\/span>\n                            <\/span>\n                        <\/div>\n                                    <\/div>\n                                    <\/a>\n                            <\/div>\n                    \n            <div class=\"product-card bg-white rounded-[7px] overflow-hidden\">\n                                    <a href=\"https:\/\/www.perimed-instruments.com\/us\/products\/accessories\/periflux-6000\/probe-404-ni\/\">\n                                                    <div class=\"aspect-w-16 aspect-h-9\">\n                        <img decoding=\"async\" src=\"https:\/\/www.perimed-instruments.com\/us\/wp-content\/uploads\/sites\/3\/laser-doppler-probe-404-ni.webp\" alt=\"Laser Doppler Probe 404-NI\" class=\"object-cover w-full h-full\">\n                    <\/div>\n                \n                <div class=\"p-6\">\n                    <div style=\"display: none;\">product-type <\/div>\n                    \n                    <h3 class=\"pb-2\">\n                        Laser Doppler Probe 404-NI\n                    <\/h3>\n\n                                            <div class=\"text-black mb-8 text-lg product-excerpt\">\n                            A low-profile laser Doppler probe designed for noninvasive measurement of blood perfusion such as SPP.\n                        <\/div>\n                    \n                                            <div>\n                            <span class=\"inline-flex items-center text-black product-read-more-link\">\n                                <span class=\"mr-6 font-medium\">\n                                    Show product\n                                <\/span>\n                                <img decoding=\"async\" src=\"https:\/\/www.perimed-instruments.com\/us\/wp-content\/themes\/perimed\/public\/images\/arrow-right.d1b3f7.svg\" alt=\"Arrow right\" class=\"mt-1 w-4 h-4\">\n                                <span class=\"sr-only\">about Laser Doppler Probe 404-NI<\/span>\n                            <\/span>\n                        <\/div>\n                                    <\/div>\n                                    <\/a>\n                            <\/div>\n                    \n            <div class=\"product-card bg-white rounded-[7px] overflow-hidden\">\n                                    <a href=\"https:\/\/www.perimed-instruments.com\/us\/applications\/clinical-and-clinical-research\/wound-healing\/\">\n                                                    <div class=\"aspect-w-16 aspect-h-9\">\n                        <img decoding=\"async\" src=\"https:\/\/www.perimed-instruments.com\/us\/wp-content\/uploads\/sites\/3\/wound-healing-1.webp\" alt=\"Wound healing\" class=\"object-cover w-full h-full\">\n                    <\/div>\n                \n                <div class=\"p-6\">\n                    <div style=\"display: none;\">application_cat Clinical<\/div>\n                                            <div class=\"category-title application-category\">\n                            <span class=\"mt-2\">Clinical<\/span>\n                        <\/div>\n                    \n                    <h3 class=\"pb-2\">\n                        Wound healing\n                    <\/h3>\n\n                                            <div class=\"text-black mb-8 text-lg product-excerpt\">\n                            Conditions like diabetes and PAD affect healing potential as they lower the level of essential oxygen and nutrients at the wound site.\n                        <\/div>\n                    \n                                            <div>\n                            <span class=\"inline-flex items-center text-black product-read-more-link\">\n                                <span class=\"mr-6 font-medium\">\n                                    Read more\n                                <\/span>\n                                <img decoding=\"async\" src=\"https:\/\/www.perimed-instruments.com\/us\/wp-content\/themes\/perimed\/public\/images\/arrow-right.d1b3f7.svg\" alt=\"Arrow right\" class=\"mt-1 w-4 h-4\">\n                                <span class=\"sr-only\">about Wound healing<\/span>\n                            <\/span>\n                        <\/div>\n                                    <\/div>\n                                    <\/a>\n                            <\/div>\n                    \n            <div class=\"product-card bg-white rounded-[7px] overflow-hidden\">\n                                    <a href=\"https:\/\/www.perimed-instruments.com\/us\/applications\/clinical-and-clinical-research\/diabetic-foot\/\">\n                                                    <div class=\"aspect-w-16 aspect-h-9\">\n                        <img decoding=\"async\" src=\"https:\/\/www.perimed-instruments.com\/us\/wp-content\/uploads\/sites\/3\/diabetic-foot.webp\" alt=\"Diabetic foot\" class=\"object-cover w-full h-full\">\n                    <\/div>\n                \n                <div class=\"p-6\">\n                    <div style=\"display: none;\">application_cat Clinical<\/div>\n                                            <div class=\"category-title application-category\">\n                            <span class=\"mt-2\">Clinical<\/span>\n                        <\/div>\n                    \n                    <h3 class=\"pb-2\">\n                        Diabetic foot\n                    <\/h3>\n\n                                            <div class=\"text-black mb-8 text-lg product-excerpt\">\n                            A serious and painful condition that is more prevalent in people with diabetes and can lead to amputation.\n                        <\/div>\n                    \n                                            <div>\n                            <span class=\"inline-flex items-center text-black product-read-more-link\">\n                                <span class=\"mr-6 font-medium\">\n                                    Read more\n                                <\/span>\n                                <img decoding=\"async\" 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wp-block-column-is-layout-flow\">\n<p class=\"has-white-color has-text-color has-link-color has-subheader-font-size wp-elements-d460a9b4f2d432b35f4358244135c513 wp-block-paragraph\">Contact us<\/p>\n\n\n\n<h2 id=\"h-get-in-touch\" class=\"wp-block-heading has-white-color has-text-color has-link-color wp-elements-bfc417e7fcd8a288654163d5827f9873\">Get in touch<\/h2>\n\n\n\n<div class=\"wp-block-group is-content-justification-left is-layout-constrained wp-container-core-group-is-layout-c898036f wp-block-group-is-layout-constrained\">\n<p class=\"has-white-color has-text-color has-link-color has-p-big-font-size wp-elements-6ac75682bd682c8e0445fd2583ced1c2 wp-block-paragraph\">If you would like to know more about how to use skin perfusion pressure, its application, or our related products, fill out the form and we will be in touch with you shortly.<\/p>\n<\/div>\n\n\n<div class=\"gn-spacer-block pb-10\">\n    <\/div>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/www.perimed-instruments.com\/contact\/distributors\/\">Or locate your nearest distributor<\/a><\/div>\n<\/div>\n\n\n<div class=\"gn-spacer-block pb-10\">\n    <\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\"><div class=\"forms-block \" >\n            <div class=\"hs-form-frame\" data-region=\"na1\" data-form-id=\"e8e7b983-6449-44dc-a412-93c18c060218\" data-portal-id=\"19961763\"><\/div>\n    <\/div>\n<\/div>\n<\/div>\n\n\n        <\/div>\n    <\/section>\n\n\n<section class=\"relative w-full references mx-auto pt-12 2xl:pt-12 pb-12 2xl:pb-12 none\" id=\"references\">\n                        \n\n        <div class=\"section__content  max-w-screen-xl px-4 mx-auto sec_no_tabs\" >\n            \n\n<p class=\"has-p-big-font-size wp-block-paragraph\"><strong>References<\/strong><\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li class=\"has-xs-font-size\">Gornik, H. L., Aronow, H. D., Goodney, P. P., Arya, S., Brewster, L. P., Byrd, L., Chandra, V., Drachman, D. E., Eaves, J. M., Ehrman, J. K., Evans, J. N., Getchius, T. S. D., Guti\u00e9rrez, J. A., Hawkins, B. M., Hess, C. N., Ho, K. J., Jones, W. S., Kim, E. S. H., Kinlay, S., Kirksey, L., \u2026 Wilkins, L. R. (2024). 2024 ACC\/AHA\/AACVPR\/APMA\/ABC\/SCAI\/SVM\/SVN\/SVS\/SIR\/VESS Guideline for the Management of Lower Extremity Peripheral Artery Disease: A Report of the American College of Cardiology\/American Heart Association Joint Committee on Clinical Practice Guidelines.&nbsp;<em>Circulation<\/em>,&nbsp;<em>149<\/em>(24), e1313\u2013e1410. <a href=\"https:\/\/doi.org\/10.1161\/CIR.0000000000001251\">https:\/\/doi.org\/10.1161\/CIR.0000000000001251<\/a><\/li>\n\n\n\n<li class=\"has-xs-font-size\">International Working Group on the Diabetic Foot (IWGDF). Guidelines on the prevention and management of diabetic foot disease (2023 update). <a href=\"https:\/\/iwgdfguidelines.org\">https:\/\/iwgdfguidelines.org<\/a><\/li>\n\n\n\n<li class=\"has-xs-font-size\">Pan, X., Chen, G., Wu, P., Han, C., &amp; Ho, J.K. (2018). Skin perfusion pressure as a predictor of ischemic wound healing potential (Review). Biomedical Reports, 8, 330-334.&nbsp;<a href=\"https:\/\/doi.org\/10.3892\/br.2018.1064\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/doi.org\/10.3892\/br.2018.1064<\/a><\/li>\n<\/ol>\n\n\n        <\/div>\n    <\/section>\n","protected":false},"excerpt":{"rendered":"<p>SPP is a noninvasive method that leverages laser Doppler to measure blood perfusion in the microcirculation. It is primarily used in clinical (and clinical research) settings to assess wound healing potential \u2014 especially in patients with chronic conditions such as diabetic foot.<\/p>\n","protected":false},"featured_media":1706,"parent":1033,"menu_order":0,"template":"","meta":{"_acf_changed":true,"inline_featured_image":false,"_FSMCFIC_featured_image_caption":"","_FSMCFIC_featured_image_nocaption":"","_FSMCFIC_featured_image_hide":""},"application_cat":[31],"class_list":["post-1030","application","type-application","status-publish","has-post-thumbnail","hentry","application_cat-applications-clinical-exams"],"acf":{"page_layout":"fullwidth","page_header_style":"dark","page_hero_overlap_header":"no","page_custom_css":""},"_links":{"self":[{"href":"https:\/\/www.perimed-instruments.com\/us\/wp-json\/wp\/v2\/application\/1030","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.perimed-instruments.com\/us\/wp-json\/wp\/v2\/application"}],"about":[{"href":"https:\/\/www.perimed-instruments.com\/us\/wp-json\/wp\/v2\/types\/application"}],"up":[{"embeddable":true,"href":"https:\/\/www.perimed-instruments.com\/us\/wp-json\/wp\/v2\/application\/1033"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.perimed-instruments.com\/us\/wp-json\/wp\/v2\/media\/1706"}],"wp:attachment":[{"href":"https:\/\/www.perimed-instruments.com\/us\/wp-json\/wp\/v2\/media?parent=1030"}],"wp:term":[{"taxonomy":"application_cat","embeddable":true,"href":"https:\/\/www.perimed-instruments.com\/us\/wp-json\/wp\/v2\/application_cat?post=1030"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}