{"id":886,"date":"2024-12-19T16:47:46","date_gmt":"2024-12-19T16:47:46","guid":{"rendered":"http:\/\/www.perimed-instruments.com\/us\/?post_type=application&p=886"},"modified":"2025-02-19T10:13:52","modified_gmt":"2025-02-19T10:13:52","slug":"clinical-research-protocols","status":"publish","type":"application","link":"https:\/\/www.perimed-instruments.com\/us\/applications\/clinical-and-clinical-research\/clinical-research-protocols\/","title":{"rendered":"Clinical research"},"content":{"rendered":"
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Home<\/a><\/span> \/ Applications<\/a><\/span> \/ Clinical<\/a><\/span> \/ Clinical research<\/span><\/span><\/div>\n\n\n

Clinical research<\/h1>\n\n\n\n

Built on advanced signal processing and laser Doppler technology, our solutions provide comprehensive insights into macro- and microcirculation. They can be used in a range of clinical research applications, including dermatology, endothelial dysfunction, and exercise physiology. Our technologies are designed to facilitate data collection and generate robust insights that help clinical researchers deliver data-driven findings.<\/p>\n\n\n

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Iontophoresis<\/h3>\n\n\n\n

Iontophoresis is a useful clinical research method that provides a noninvasive means to deliver certain types of drugs directly through the skin. <\/p>\n\n\n\n

The process is easy to carry out, it supports precise, localized delivery, and is painless for the study participant. <\/p>\n\n\n\n

Combining laser speckle measurement with iontophoresis enables researchers to assess the impact of drugs and novel compounds on the microcirculation in real-time.<\/p>\n\n\n

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Our iontophoresis solutions<\/a><\/div>\n<\/div>\n\n\n
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Post-occlusive reactive hyperemia (PORH)<\/h3>\n\n\n\n
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PORH is a noninvasive method used to investigate and assess microvascular function. The exam involves taking blood perfusion measurements before, during, and after a prolonged occlusion.<\/p>\n\n\n\n

To avoid undue patient discomfort, pressure exams involving occlusion typically last up to about one minute in clinical settings. In a PORH exam, however, the typical occlusion time is around 5 minutes. After the pressure in the cuff is released, the hyperemic response is measured, which reflects vascular reactivity and the capacity of the blood vessels to dilate and restore perfusion. The recovery phase is often monitored for several minutes.<\/p>\n\n\n\n

In clinical research, PORH could be used to: <\/p>\n\n\n\n