Exercise physiology is the field of medicine that studies the effects on, and adaptations of, the body due to physical activity. There are many areas of interest in this field that can use Laser Doppler Flowmetry (LDF) for clinical research purposes, including thermoregulation, cutaneous vasodilatation, and heat stress. Both healthy and diseased populations are of interest, as this research can apply to improving athlete performance, and better understanding the effects or mechanisms of a specific disease.
In this field, LDF is typically used to measure changes in skin blood flow, as the microcirculation is of particular interest. This is often done in conjunction with a heated probe, either to illicit a thermoregulatory response (with a probe temperature higher than skin temperature) or to maintain consistent experimental conditions (with a probe temperature equal to skin temperature). Post-occlusive reactive hyperemia (PORH) is another measurement technique that is used in conjunction with LDF in exercise physiology.