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Post Occlusive Reactive Hyperemia

Post occlusive reactive hyperemia (PORH) is used to investigate and assess microvascular function (endothelial function). The test involves blood perfusion measurements before, during and after occlusion.

The PeriFlux System 5000 with a standard laser Doppler probe and cuff can be used to monitor a PORH reaction. In this case, the laser Doppler probe is placed distal to the cuff which is then inflated to a pressure well above the systolic blood pressure. After 3 to 5 minutes occlusion, pressure is released instantly and the laser Doppler signal is evaluated. Important parameters to evaluate include time to resting perfusion, time to half recovery, percentage change from baseline, maximum perfusion and area under curve.

Features:

  • Automatic generation of PORH specific report
  • Possibility of adding other complementary techniques such as heat-controlled laser Doppler

The PeriFlux System 5000 is not available within the EU and the EEA.


Another option to study post occlusive reactive hyperemia (PORH) is using the microcirculatory imager PeriCam PSI System. Equipped with a CCD camera that can capture images with a speed of up to 100 fps, PeriCam PSI System can both monitor the dynamics of the response as well as generating a spatial view of the blood distribution in a given area.

Features:

  • Laser Speckle technology
  • Video speed, large areas



Endothelial Dysfunction

Post-Occlusive Reactive Hyperemia is an objective method to study the endothelium and assess the subject's endothelium dependent and endothelium independent vasodilation when subjected to local heating.

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Improving quality of life since 1981

Perimed AB, established in 1981, provides instruments, software and expertise to enable assessment of the microcirculation. We utilize laser Doppler, laser speckle (LASCA) and transcutaneous oxygen (tcpO2 or TCOM), to accurately monitor and quantify blood perfusion and tissue oxygenation in real-time. Our modular PeriFlux System 5000 and PeriFlux 6000, the latest generation of our PeriFlux System, are excellent choices for diagnosing Peripheral Arterial Disease (PAD) and Critical Limb Ischemia (CLI) or for assessing wound healing potential in your vascular patients. Our blood perfusion imagers PeriScan PIM 3 System and PeriCam PSI System, allow you to investigate spatial distribution, for example during cortical spreading depression.