Microcirculation is crucial for delivering oxygen and nutrients to tissues and removing waste products. This fine-scale blood flow reflects underlying vascular health and is increasingly recognized as a sensitive marker of systemic diseases, including diabetes and peripheral artery disease (PAD).
In clinical assessment, monitoring microcirculation provides insight into a patient’s vascular health and tissue viability, offering early indications of disease onset and progression and enabling targeted interventions.
In clinical research, microcirculation measurements are fundamental for understanding the effects of diseases and treatments on the vascular system. Advanced imaging technologies, like laser speckle contrast imaging, allow researchers to track changes in microvascular function over time, supporting the development of new therapies and diagnostic tools. By accurately assessing microcirculation, clinical researchers can link microvascular function to clinical outcomes, improving the predictive value of studies and contributing to the advancement of personalized medicine.
Peripheral artery disease (PAD) affects over 113 million people globally, contributing to pain, disability, and, in severe cases, amputation. Early detection and accurate monitoring are critical for managing this chronic condition.
Wound healing can be complex and unpredictable. Stakes are high when healing slows or stalls and every wound presents unique challenges. While foundational methods like visual inspections and touch tests like capillary refill are part of everyday practice, not all wounds respond the same.
Early detection of complications in diabetic foot are crucial to prevent severe outcomes and save limbs.
Some of our products used in clinical and clinical research applications.*
*not all products are cleared for clinical use or clinical research in all regions. Contact us for more details.
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LASCA and LSCI
Laser speckle contrast imaging (LSCI) is the innovative technology behind PeriCam PSI, offering non-contact, high-resolution perfusion imaging. The technique was first described by J.D. Briers and S. Webster in 1996 and referred to as laser speckle contrast analysis (LASCA). In later years, the term LSCI gained in popularity and is nowadays the more common term. However, LSCI and LASCA both refer to the same technique, providing precise and reliable perfusion data without the need for contrast agents.
